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Found 11 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2b' and Ligand = 'BDBM50042209'
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]ZM241385 from human recombinant Adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53nMAssay Description:Antagonist activity at human A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor was measured by the inhibition of isoproterenol-induced relaxation of PGF2-alpha cont...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]ZM241385 from recombinant human A2B adenosine receptor expressed in CHO cell membranes measured after 30 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53.4nMAssay Description:Binding affinity for human adenosine A2B receptor using [3H]-ZM-241,385 in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  53.4nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  191nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cell membrane preincubated for 4 hrs followed by [3H]PSB-603 addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  195nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptor expressed in CHO cell membrane and measured after 0.5 hrs by radioligand displacement a...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2b(Mus musculus)
Rheinische Friedrich-Wilhelms-Universitat Bonn

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  1.94E+3nMAssay Description:Displacement of [3H]PSB-603 from recombinant mouse A2B adenosine receptor expressed in CHO cell membranes measured after 75 mins by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Rattus norvegicus)
Rheinische Friedrich-Wilhelms-Universitat Bonn

Curated by ChEMBL
LigandPNGBDBM50042209(4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-...)
Affinity DataKi:  3.14E+3nMAssay Description:Displacement of [3H]PSB-603 from recombinant rat A2B adenosine receptor expressed in CHO cell membranes measured after 75 mins by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed