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Found 6 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 17' and Ligand = 'BDBM50106017'
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  6.5nMAssay Description:Concentration required to inhibit the release of tumor necrosis factor -alpha (TNF-alpha) in THP-1 cellular assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  4.10E+4nMAssay Description:Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50106017(CHEMBL421009 | N-Hydroxy-2-methyl-3-[4-(3,4,5-trim...)
Affinity DataIC50:  4.10E+4nMAssay Description:Concentration required to inhibit the release of tumor necrosis factor -alpha (TNF-alpha) in THP-1 cellular assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed