Found 5 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50187377'
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Predix Pharmaceuticals
Curated by ChEMBL
Predix Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity to 5HT1A receptor in rat cerebral cortex by radioligand binding assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Predix Pharmaceuticals
Curated by ChEMBL
Predix Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 93nMAssay Description:Agonist activity at human 5HT1A receptor expressed in C6 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Activity against 5HT1A receptor by Gi-[35S]GTPgammaS binding assayMore data for this Ligand-Target Pair