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Found 9 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1D' and Ligand = 'BDBM50060425'
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50:  0.5nMAssay Description:Affinity of compound towards 5-hydroxytryptamine 1D receptor was evaluated using radioligand binding techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity by displacement to human cloned 5-hydroxytryptamine 1D receptor in CHO cells by [3H]-5-HT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]-5-HT binding from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataIC50:  0.600nMAssay Description:Ability to displace [3H]- -5-HT binding to cloned 5-hydroxytryptamine 1D receptor stably expressed in chinese hamster cells (CHO cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.800nMAssay Description:Measurement of agonist induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.800nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.800nMAssay Description:Stimulation of [35S]-GTP-gammaS, binding in CHO cells expressing the 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50060425(Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3...)
Affinity DataEC50:  0.930nMAssay Description:Measurement of agonist induced [35S]-GTP-gammaS, binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed