Found 13 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A/3B' and Ligand = 'BDBM50014407'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heartMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptor in the rabbit heartMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.447nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Homo sapiens (Human))
Universita' Degli Studi Di Salerno
Curated by ChEMBL
Universita' Degli Studi Di Salerno
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]-guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Mus musculus (house mouse))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKd: 2nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heartMore data for this Ligand-Target Pair