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Found 9 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A/3B' and Ligand = 'BDBM82561'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  24nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  26nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  54nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  55nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]Q-ICS-205-930 from 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Istituto De Angeli

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataIC50:  43nMAssay Description:Binding affinity was evaluated in vitro by displacement of [3H]zacopride radioligand from 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Mus musculus (house mouse))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed