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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50436989'
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL
LigandPNGBDBM50436989(CHEMBL2402904)
Affinity DataEC50:  2.5nMAssay Description:Induction of 5-HT4 receptor-mediated contraction in guinea pig longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Theravance

Curated by ChEMBL
LigandPNGBDBM50436989(CHEMBL2402904)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at 5-HT4 receptor in guinea pig colonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50436989(CHEMBL2402904)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed