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Found 4 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50113626'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113626(CHEMBL3604634)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human wild type ALK using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113626(CHEMBL3604634)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type human recombinant ALK using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113626(CHEMBL3604634)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human ALK L1196M mutant using tyrosine kinase substrate-biotin after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Beijing Pearl Biotech

Curated by ChEMBL
LigandPNGBDBM50113626(CHEMBL3604634)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) using TK substrate-biotin incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed