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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50370885'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50370885(CHEMBL375243)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50370885(CHEMBL375243)
Affinity DataEC50:  6nMAssay Description:Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed