Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50538595' TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM...More data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs b...More data for this Ligand-Target Pair
