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Found 4 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50235196'
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50235196(CHEMBL4064760)
Affinity DataIC50:  37nMAssay Description:Inhibition of human ROMK expressed in CHO cells by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50235196(CHEMBL4064760)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50235196(CHEMBL4064760)
Affinity DataIC50:  44nMAssay Description:Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50235196(CHEMBL4064760)
Affinity DataIC50:  44.1nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair
In DepthDetails US Patent