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Found 3 Enz. Inhib. hit(s) with Target = 'Acyl-CoA desaturase 1' and Ligand = 'BDBM50443725'
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443725(CHEMBL3093865 | US9238658, 4)
Affinity DataIC50:  502nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443725(CHEMBL3093865 | US9238658, 4)
Affinity DataIC50:  538nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using Stearoyl-[9,10-3H]-CoA as substrate assessed as [3H2O] generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443725(CHEMBL3093865 | US9238658, 4)
Affinity DataIC50:  573nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 uL using 10 ug of RLM (prepared as described above) in a 96-well polypropylene plate (enzyme reac...More data for this Ligand-Target Pair
In DepthDetails US Patent