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Found 4 Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type 1' and Ligand = 'BDBM50052121'
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataIC50: >150nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataIC50:  185nMAssay Description:Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataEC50:  3.60E+3nMAssay Description:Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1(Homo sapiens (Human))
Food And Drug Administration

Curated by ChEMBL
LigandPNGBDBM50052121(3-((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihy...)
Affinity DataEC50: >2.00E+3nMAssay Description:Ability to activate the conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed