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Found 2 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B1' and Ligand = 'BDBM50009835'
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009835(4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1...)
Affinity DataIC50:  110nMAssay Description:Percent inhibition of sorbitol accumulation in rat lens was measuredChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009835(4-Hydroxy-5-oxo-1-pyridin-4-ylmethyl-2,5-dihydro-1...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human placental aldose reductase.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed