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Found 3 Enz. Inhib. hit(s) with Target = 'Alpha-synuclein' and Ligand = 'BDBM50389294'
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389294(CHEMBL2063787)
Affinity DataKi:  32.1nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389294(CHEMBL2063787)
Affinity DataIC50:  134nMAssay Description:Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50389294(CHEMBL2063787)
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed