Found 89 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] A' and Ligand = 'BDBM15579' 
Affinity DataKi: 3.80E+3nM ΔG°: -32.3kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of bovine brain MAOA using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of bovine brain mitochondrial MAO-A by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.70E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
Affinity DataKi: 8.15E+3nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
Affinity DataKi: 9.06E+3nMAssay Description:Competitive reversible inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 insect cells using p-tyramine as substrate assesse...More data for this Ligand-Target Pair
Affinity DataKi: 9.06E+3nMAssay Description:Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 minsMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 1.06E+4nMAssay Description:Competitive inhibition of rat liver MAO-A after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 1.57E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.69E+4nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as H2O2 production preincubated for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
Affinity DataKi: 2.81E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate incubated for 30 mins by Ample...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:Inhibitory activity against monoamine oxidase A in isolated bovine brain mitochondriaMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:Inhibtory concentration for rat Monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataKi: 6.73E+4nMAssay Description:Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 1.06E+5nMAssay Description:Competitive inhibition of MAOA in rat liver homogenate by spectrophotometricallyMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 1.06E+5nMAssay Description:Inhibition of MAO-A in rat liver homogenate by spectrophotometry-based Holt methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of rat brain synaptosome MAO-AMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MAO-A in rat whole brain homogenate in presence of selegilineMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 67.3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-tyramin...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 516nMAssay Description:In vitro ability of the compound to inhibit Monoamine oxidase A activity in rat whole brain in vitroMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Compound was evaluated for the time-dependence inhibition of MAO-A at 60 minutes of preincubated period. values are same with or without pre-incubati...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory activity on rat brain by monoamine oxidase A (MAO-A)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 944nMAssay Description:Inhibition of rat brain MAO-A using [14C]-5- hydroxytryptamine creatinine disulphate substrate after 30 minsMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 969nMAssay Description:Inhibition of Sprague-Dawley rat liver MAO-A using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MAOAMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]-Ro 41-1049 from MAO-A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Irreversible inhibition of human cerebral cortex MAO-A using [14C]-5-hydroxytryptamine creatinine disulphate as substrate pretreated for 60 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human brain MAO-A using [14C]-5- hydroxytryptamine creatinine disulphate substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant MAO-A preincubated for 30 mins followed by p-tyramine hydrochloride addition measured after 30 mins by Amplex red flu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using tyramine as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Birla Institute Of Technology
Curated by ChEMBL
Birla Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Monoamine oxidase A of rat liver mitochondrial membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation using...More data for this Ligand-Target Pair
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of human recombinant MAOA using kynuramine substrate incubated for 20 mins by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected insect cell membranes using kynuramine as substrate after 15 to 20 mins by discontinuous ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of bovine mitochondrial MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.79E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.43E+4nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 5.44E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cells using p-tyramine as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of human recombinant MAOA using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 1 hr by horse...More data for this Ligand-Target Pair
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of recombinant human MAOA using p-tyramine as substrate assessed as H2O2 production preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.27E+4nMAssay Description:Inhibition of recombinant human microsomal MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.28E+4nMAssay Description:Inhibition of human MAO-A assessed as inhibition of H2O2 production using p-tyramine as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.36E+4nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI-TN-5B1-4 cells using p-tyramine substrate assessed as reduction in H2O2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in BTI cellsMore data for this Ligand-Target Pair
