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Found 3 Enz. Inhib. hit(s) with Target = 'Amine oxidase [flavin-containing] B' and Ligand = 'BDBM50145630'
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50145630(CHEMBL3764447)
Affinity DataKi:  3.5nMAssay Description:Competition inhibition of recombinant human MAO-B pretreated with compound for 15 mins followed by addition of 50 uM kynuramine as substrate by Linew...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50145630(CHEMBL3764447)
Affinity DataKi:  3.90nMAssay Description:Inhibition of recombinant human MAO-B pretreated with compound for 15 mins followed by addition of 50 uM kynuramine as substrate by Michaelis-Menten ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50145630(CHEMBL3764447)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human MAO-B after 20 mins using 50 uM kynuramine as substrate by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed