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Found
1
Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM200313'
Target
Amyloid-beta precursor protein
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM200313
(US9226927, 25h)
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Affinity Data
IC50: 16.5nM
pH: 7.0 T: 2°C
Assay Description:
To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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US Patent
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