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Found 1 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM200313'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200313(US9226927, 25h)
Affinity DataIC50:  16.5nMpH: 7.0 T: 2°CAssay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent