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Found 5 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50012653'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild type human APP expressed in CHO cells assessed as reduction in amyloid beta 40 secretion incubated for 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild type human APP expressed in CHO cells assessed as reduction in amyloid beta 42 secretion incubated for 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50:  3nMAssay Description:Inhibition of wild type human APP751 expressed in CHO cells incubated for 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50:  4nMAssay Description:Inhibition of wild type human APP expressed in CHO cells assessed as reduction in soluble APP beta level incubated for 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50:  98nMAssay Description:Inhibition of wild type APP751 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed