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Found 5 Enz. Inhib. hit(s) with Target = 'Androgen receptor' and Ligand = 'BDBM50157821'
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157821((2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-aza...)
Affinity DataKi:  9nMAssay Description:Binding affinity for mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157821((2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-aza...)
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity for androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157821((2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-aza...)
Affinity DataIC50:  30nMAssay Description:Inhibition of mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157821((2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-aza...)
Affinity DataIC50:  148nMAssay Description:Inhibition of androgen dependent human prostate cancer cell MDA-MB-PCa2b proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50157821((2R,6S,8S,10R)-4-[3-(trifluoromethyl)phenyl]-4-aza...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed