Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Aromatase' and Ligand = 'BDBM50388393'
TargetAromatase(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataKi:  86nMAssay Description:Inhibition of aromatase in human microsomes using [1beta-3H]androstenedione as substrate after 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50:  970nMAssay Description:Inhibition of aromatase in human placental microsomes using [1beta-3H]androstenedione as substrate after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of aromatase in disrupted human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrs in the presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
University Of Coimbra

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed