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Found 2 Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50352304'
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50352304(CHEMBL1822643)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of Aurora B kinase assessed as reduction in histone H3 phosphorylation in human HCT116 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50352304(CHEMBL1822643)
Affinity DataKd:  69nMAssay Description:Binding affinity to Aurora B kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed