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Found 2 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50269559'
TargetBeta-secretase 1(Homo sapiens (Human))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50269559(2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKi:  8.26E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE-1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50269559(2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  6.06E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed