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Found 4 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50380548'
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50380548(CHEMBL2019055)
Affinity DataKi:  1.60nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50380548(CHEMBL2019055)
Affinity DataKi:  9.70nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50380548(CHEMBL2019055)
Affinity DataIC50:  2nMAssay Description:Inhibition of Homo sapiens (human) Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50380548(CHEMBL2019055)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed