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Found 3 Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50393104'
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of BACE by secreted APPbeta release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of BACE by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50:  1.60nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In DepthDetails US Patent