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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) with Target = 'Beta-secretase 1 [1-460]' and Ligand = 'BDBM376564'
Target
Beta-secretase 1 [1-460]
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM376564
(US9918985, Example 20a Isomer 1)
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Affinity Data
IC50: 0.570nM
Assay Description:
The enzyme (truncated form) was diluted to 6 μg/mL (stock 1.3 mg/mL) and the substrate (Europium)CEVNLDAEFK(Qsy7) to 200 nM (stock 120 μM) ...
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