TargetBeta-secretase 2(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H] JNJ-962 from BACE2 (unknown origin) expressed in HEK293 cell membranes assessed as inhibition constant at pH 6.2 by scintillatio...More data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of BACE2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of BACE2 (unknown origin) using APP harboring Swedish Lys/Met mutant-derived peptide as substrate by FRET assayMore data for this Ligand-Target Pair