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Found 8 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM50029772'
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  7.40nMAssay Description:Concentration inhibiting T. gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  7.40nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50029772(5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against cultured Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed