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Found 4 Enz. Inhib. hit(s) with Target = 'Bifunctional dihydrofolate reductase-thymidylate synthase' and Ligand = 'BDBM50034940'
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50034940(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50034940(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50:  29nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50034940(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50:  29nMAssay Description:The compound was tested for inhibition of dihydrofolate reductase(DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50034940(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against Dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed