Found 5 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50022815' TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hungarian Academy Of Sciences
Curated by ChEMBL
Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:TP_TRANSPORTER: inhibition of ATPase in membrane vesicle from BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hungarian Academy Of Sciences
Curated by ChEMBL
Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in human HEK293 cells mediated pheophorbide A efflux and measured after 90 mins by FACSflow cytometryMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hungarian Academy Of Sciences
Curated by ChEMBL
Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >6.57E+3nMAssay Description:Inhibition of sulfasalazine-stimulated BCRP ATP ase activity (unknown origin)More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hungarian Academy Of Sciences
Curated by ChEMBL
Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of ABCG2 in human mitoxantrone-resistant MCF7 cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Hungarian Academy Of Sciences
Curated by ChEMBL
Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 1.75E+3nMAssay Description:Inhibition of BCRP (unknown origin) transfected in HEK293/R2 cells assessed as reversal of topotecan resistance after 5 days by MTS/PMS assayMore data for this Ligand-Target Pair
