Found 12 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50208999' TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis after 30 mins by Celltiter-glo reagent based luminescence assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CCR1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP1alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Antagonist activity against human CCR1 receptor expressed in THP1 cells assessed as inhibition of chemotaxisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Binding Affinity at CCL3More data for this Ligand-Target Pair
Affinity DataIC50: 615nMAssay Description:Binding affinity at mouse CCR1More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to mouse CCR1 by radioligand binding assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 1(Homo sapiens (Human))
National Heart And Lung Institute
Curated by ChEMBL
National Heart And Lung Institute
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Binding affinity to human CCR1 by radioligand binding assayMore data for this Ligand-Target Pair
