Found 13 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50163634'
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Rattus norvegicus)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of rat eosinophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophil at 30 nMMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-eotaxin binding to human eosinophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of calcium mobilization in human eosinophilsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair