Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50441704'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441704(CHEMBL2435892)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in human HeLa cells assessed as inhibition of interaction of CHO cells expressing HIV-1 JRFLenv and HIV...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441704(CHEMBL2435892)
Affinity DataIC50:  5.80nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293F cell membranes assessed as inhibition of RANTES-induced calcium flux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441704(CHEMBL2435892)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]-RANTES from CCR5 (unknown origin) expressed in HEK293F cell membranes after 45 mins by microbeta jet liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed