Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 5' and Ligand = 'BDBM50506124'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at human TEV cleavage site-linked CCR5 expressed in human U2OS cells harboring beta-lactamase reporter gene assessed as inhibitio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  5nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  8.90nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  9nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  6.20nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as pEC50 for CCL3-stimulated [35S]GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506124(CHEMBL4544504)
Affinity DataEC50:  6nMAssay Description:Non-competitive insurmountable antagonist activity at human CCR5 expressed in human U2OS cell membranes assessed as EC50 for CCL3-stimulated [35S]GTP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed