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Found 6 Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 3' and Ligand = 'BDBM50375116'
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Mus musculus)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  70nMAssay Description:Displacement of [125I]-CXCL10 from mouse CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Mus musculus)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375116(CHEMBL403290)
Affinity DataIC50:  80nMAssay Description:Displacement of [125I]-CXCL10 from mouse CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed