Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7' and Ligand = 'BDBM50528812'
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataKi:  17nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) in leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50:  84nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrate in presence of Km ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50:  84nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) pre incubated up to 60 mins followed by substrate and ATP additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50:  590nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin) using 5-FAM YSPTSPSYSPTSPSYSPTSPSKKKK as substrate in presence of 2 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataEC50:  13nMAssay Description:Competitive irreversible inhibition of CDK7/cyclinH/MAT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed