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Found 2 Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50301971'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50301971(2-((S)-6-(2,6-difluorophenyl)-3,3-dimethyl-2-oxopi...)
Affinity DataKi:  0.0350nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50301971(2-((S)-6-(2,6-difluorophenyl)-3,3-dimethyl-2-oxopi...)
Affinity DataIC50:  0.120nMAssay Description:Antagonist activity at human cloned CGRP receptor expressed in HEK293 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed