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Found 10 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM21283'
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]-CP55940 from CB1 receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  580nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  580nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  1.27E+3nM ΔG°:  -34.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  2.08E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  5.00E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataIC50:  280nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed