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Found 7 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM21311'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  845nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  845nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataKi:  945nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataIC50:  330nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataIC50:  330nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataEC50:  811nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM21311(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Affinity DataEC50:  248nMAssay Description:Agonist activity at rat CB1 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed