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Found 5 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM50042659'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50042659(CHEMBL3353870 | Example 190 in WO2010077836 | US10...)
Affinity DataIC50:  7.87E+3nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50042659(CHEMBL3353870 | Example 190 in WO2010077836 | US10...)
Affinity DataEC50:  438nMAssay Description:CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50042659(CHEMBL3353870 | Example 190 in WO2010077836 | US10...)
Affinity DataEC50:  7.87E+3nMAssay Description:CHO cells expressing human CB1 R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37° C. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50042659(CHEMBL3353870 | Example 190 in WO2010077836 | US10...)
Affinity DataEC50:  7.20E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Centrexion Therapeutics

US Patent
LigandPNGBDBM50042659(CHEMBL3353870 | Example 190 in WO2010077836 | US10...)
Affinity DataEC50:  7.87E+3nMAssay Description:CB1: CHO cells expressing human CB1R (Euroscreen) were plated at a density of 10,000 cells per well in 384 well plates and incubated overnight at 37°...More data for this Ligand-Target Pair
In DepthDetails US Patent