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Found 3 Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM50272395'
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272395(CHEMBL499066 | N-(3-(3-(2-Chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272395(CHEMBL499066 | N-(3-(3-(2-Chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50272395(CHEMBL499066 | N-(3-(3-(2-Chloro-4-fluorophenyl)-1...)
Affinity DataEC50:  850nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed