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Found 2 Enz. Inhib. hit(s) with Target = 'Caspase-3' and Ligand = 'BDBM10342'
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM10342((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azet...)
Affinity DataIC50:  11.2nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM10342((S)-1-(4-Methylthiobenzyl)-5-(2-phenoxymethyl-azet...)
Affinity DataIC50:  11.3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed