Found 17 Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase/Protein DBF4 homolog A' and Ligand = 'BDBM50016163' TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 1 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 2 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 6 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.667 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.012 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 9 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.333 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 18 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.111 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.222 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.025 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 27 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.037 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 0.074 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin) using 54 uM of ATP as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
