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Found 2 Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM202363'
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)
Affinity DataIC50:  620nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM202363(US9238626, (+/-)-(Ib) HCl)
Affinity DataIC50:  620nMpH: 8.0 T: 2°CAssay Description:BChE inhibitory activity determinations were carried out similarly by the method of Ellman et al., using 0.02 unit/mL of human serum BChE and 300 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent