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Found 5 Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50218282'
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  0.730nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of human factor 10a in presence of prothrombin at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  30nMAssay Description:Inhibition of human factor 10a in presence of saturating prothrombin at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed