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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM289850'
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM289850(N—((S)-1-((R)-6-chloro-5-fluoro-2-oxo-1,2-dih...)
Affinity DataKi: >875nM ΔG°: >-34.6kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent