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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM357188'
Target
Coagulation factor XI
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM357188
(US10214512, Example 143-b)
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Affinity Data
Ki: 0.100nM
Assay Description:
The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...
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