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Found 3 Enz. Inhib. hit(s) with Target = 'Cocaine esterase' and Ligand = 'BDBM50130915'
TargetCocaine esterase(Homo sapiens (Human))
Liaoning University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibition of human carboxylesterase 2 using 4-benzoyl-N-butyl-1,8-naphthalimide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Liaoning University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  6.11E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Liaoning University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed