Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Collagenase 3' and Ligand = 'BDBM30344'
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)
Affinity DataKi:  0.530nM ΔG°:  -52.4kJ/mole IC50:  3.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)
Affinity DataKi:  1nMAssay Description:Binding affinity to recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)
Affinity DataKi:  3nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed