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Found
1
Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 6' and Ligand = 'BDBM525754'
Target
Cyclin-dependent kinase 6
(Homo sapiens (Human))
Nuvation Bio
US Patent
Ligand
BDBM525754
(US11174252, Compound 441)
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Affinity Data
IC50: 0.600nM
Assay Description:
CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...
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Target Info
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Reactome pathway
KEGG
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Ligand Info
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Details
US Patent
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